Minggu, 27 Juli 2014

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.

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As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

  • Sales Rank: #8662550 in Books
  • Published on: 2015-02-20
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.69" h x .40" w x 7.44" l, .77 pounds
  • Binding: Paperback
  • 190 pages

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Minggu, 13 Juli 2014

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This book provides a comprehensive overview of the proteases involved in programmed cell death. It presents a focused yet extensive discussion on proteolytic enzymes such as caspases, HtrAs, granzymes, calpains and cathepsins as well as laboratory protocols related to enzymology and apoptosis. Mouse model systems and non-invasive imaging techniques in apoptosis-related diseases such as cancer and neurodegeneration are also covered in this book.

While slowly unravelling the complexities of apoptosis in chapter one, the next three chapters individually elaborate on different classes of proteases that play key roles in the initiation, progression and execution of programmed cell death. The last two chapters complete this discussion by describing different laboratory methodologies and therapeutic advances involving apoptotic proteases. Protocols portraying in vitro and ex vivo colorimetric and fluorescence-based enzyme kinetic studies as well as cell death assays are explained in the fifth chapter. Preclinical in vivo models and non-invasive imaging in apoptosis to understand the complexities of disease progression and their contribution toward therapeutics is recounted in the last chapter.

The book spans topics related to both fundamental and applied biology. It would therefore be equally appealing and informative to scientists working in the field of apoptosis and those who are investigating mechanisms of proteases and enzymes in general. The protocols would certainly benefit both graduate and undergraduate students working in the related fields and provide useful leads for drug design to translational biologists involved in neurodegeneration and cancer research.

  • Published on: 2015-08-07
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.48" h x .74" w x 6.16" l, 1.45 pounds
  • Binding: Hardcover
  • 245 pages

Review

“This is a comprehensive overview of the mechanisms of apoptosis, with a particular emphasis on proteases. … The book is designed to inform and inspire undergraduate and graduate students to pursuing biomedical research. … it might be more appropriate for researchers in related fields who desire a comprehensive source of current information about apoptotic proteases … . This is a useful addition to the field and many will find it useful when preparing lectures or when working in related fields.” (Susan Viselli, Doody’s Book Reviews, November, 2015)

“This is a monograph on proteolysis via programmed cell death via caspase and granzyme mediated destruction in neurodegeneration. I recommend it for biochemists, cell biologists, & neurologists.” (Joseph J. Grenier, Amazon.com, November, 2015)

From the Back Cover

This book provides a comprehensive overview of the proteases involved in programmed cell death. It presents a focused yet extensive discussion on proteolytic enzymes such as caspases, HtrAs, granzymes, calpains and cathepsins as well as laboratory protocols related to enzymology and apoptosis. Mouse model systems and non-invasive imaging techniques in apoptosis-related diseases such as cancer and neurodegeneration are also covered in this book.

While slowly unravelling the complexities of apoptosis in chapter one, the next three chapters individually elaborate on different classes of proteases that play key roles in the initiation, progression and execution of programmed cell death. The last two chapters complete this discussion by describing different laboratory methodologies and therapeutic advances involving apoptotic proteases. Protocols portraying in vitro and ex vivo colorimetric and fluorescence-based enzyme kinetic studies as well as cell death assays are explained in the fifth chapter. Preclinical in vivo models and non-invasive imaging in apoptosis to understand the complexities of disease progression and their contribution toward therapeutics are recounted in the last chapter.

The book spans topics related to both fundamental and applied biology. It would therefore be equally appealing and informative to scientists working in the field of apoptosis and those who are investigating mechanisms of proteases and enzymes in general. The protocols would certainly benefit both graduate and undergraduate students working in the related fields and provide useful leads for drug design to translational biologists involved in neurodegeneration and cancer research.

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0 of 0 people found the following review helpful.
Apoptosis Mechanics
By Joseph J Grenier
Apoptosis Pathways

Springer international

Re; Joseph Grenier MD PHD

This is a monograph on proteolysis via programmed cell death via caspase and granzyme mediated destruction in neurodegeneration. I recommend it for biochemists, cell biologists, & neurologists.

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Sabtu, 12 Juli 2014

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La familia de George es un tanto peculiar: son vegetarianos y evitan cualquier tipo de tecnologia: por eso viven sin television, sin telefono, sin radio y sin ordenador!, por lo que George se ha ganado la fama de 'raro'. Un dia, su cerdito entra en la casa del vecino y George tiene que ir a rescatarlo. Alli conoce a Annie, una nina de su edad un tanto pretenciosa y muy mentirosa y a su padre, Eric. La casa donde viven es un pequeno 'museo de la ciencia', y lo que mas llama la atencion de George es Cosmos, el ordenador, que se presenta a si mismo como 'el mas potente del mundo'. Despues de jurar que usara la ciencia solo para buenos fines, George, de la mano de Cosmos, descubre como se crearon las estrellas.

  • Sales Rank: #1948927 in Books
  • Published on: 2010-07
  • Original language: Spanish
  • Number of items: 1
  • Dimensions: 7.75" h x 5.00" w x .50" l, .48 pounds
  • Binding: Paperback
  • 224 pages

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0 of 0 people found the following review helpful.
Muy interesante
By Michele Najlis
Muy interesante. Un libro sencillo para no especialistas,escrito de manera amena.

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Jumat, 11 Juli 2014

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  • Published on: 1709
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How to Change the World provides vivid profiles of social entrepreneurs. The book is an In Search of Excellence for social initiatives, intertwining personal stories, anecdotes, and analysis. Readers will discover how one person can make an astonishing difference in the world.
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  • Sales Rank: #9682 in Books
  • Brand: Bornstein, David
  • Published on: 2007-09-17
  • Released on: 2007-09-17
  • Original language: English
  • Number of items: 1
  • Dimensions: 6.10" h x 1.00" w x 9.00" l, 1.22 pounds
  • Binding: Paperback
  • 368 pages
Features
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  • guidance
  • inspiring features

Amazon.com Review
Book Description
Published in over twenty countries, How to Change the World has become the Bible for social entrepreneurship. It profiles men and women from around the world who have found innovative solutions to a wide variety of social and economic problems. Whether they work to deliver solar energy to Brazilian villagers, or improve access to college in the United States, social entrepreneurs offer pioneering solutions that change lives.

Discover surprising facts about social entrepreneurs from author David Bornstein

  • According to a recent Harris Poll, a whopping 97% of Generation Y are looking for work that allows them "to have an impact on the world."
  • In recent years, courses or centers in social entrepreneurship have been created in over 250 universities and colleges such as Harvard Business School, Yale School of Management, Duke, NYU's Stern & Wagner, Wharton, Oxford, and Stanford.
  • Teach for America received 25,000 applications for 3,700 slots in 2008, an increase of more than a third over 2007. In Ivy League schools such as Yale, Cornell, and Dartmouth, close to 10% of all graduates applied to the program.
  • In the past two years, the Acumen Fund, an organization that supports social entrepreneurs who solve major problems through business solutions (eg. malaria nets, water purification, loans for housing), received more than 1,000 applications from top ranked business students for just 15 fellowship positions.
  • The list of top business entrepreneurs who are focusing either full time or a considerable amount of time on social entrepreneurship is highly impressive:
  • Pierre Omidyar, founder of ebay, created Omidyar Network to "enable individual self-empowerment on a global scale."
  • Jeff Skoll, cofounder of ebay, also runs Participant Productions, which makes socially conscious films including An Inconvenient Truth and Goodnight and Good Luck.
  • Bill Gates has left Microsoft to pursue a full-time career in philanthropy.
  • Warren Buffett recently donated $30 billion to the Gates Foundation.
  • William Draper, one of the biggest venture capitalists in Silicon Valley, created the Draper Richards Foundation to support social entrepreneurs.
  • Klaus Schwab, the founder of the World Economic Forum (Davos), founded the Schwab Foundation for Social Entrepreneurship.
  • Sergey Brin and Larry Page, founders of Google, created Google.org, which supports social entrepreneurs and has raised over $1 billion.
  • Legendary venture capitalist John Doerr is leading an effort to raise $100 million for microcredit loans.
  • The Grameen Bank, the leading example for social entrepreneurs worldwide, received the Nobel Peace Prize in 2006.
  • The Bridgespan Group, a consulting group that advises social entrepreneurs, received 1,800 applications for 18 job openings in 2006.

Review
"Wonderfully hopeful and enlightening.... The stories of these social entrepreneurs will inspire and encourage many people who seek to build a better world." --Nelson Mandela
"The book is must reading for anyone who cares about building a more equitable, and therefore more stable, world."--William J. Holstein, New York Times
"I've told everyone within earshot about it. Besides, I'm confident that those who've read the earlier volume will appreciate the update...Buy extra copies of the book as gifts-someone you know may be looking for a future with meaning."--Portland Alliance
"David Bornstein's How to Change the World provides a wonderful introduction to social entrepreneurship. It is engaging, inspiring, and informative, weaving Bornstein's thoughtful commentary with a set of rich, diverse, and instructive examples. It is the first book I recommend to interested students." -- Professor J. Gregory Dees, Faculty Director, Center for the Advancement of Social Entrepreneurship, Duke University's Fuqua School of Business
"A fascinating book.... Well-documented cases of grassroots entrepreneurial activities to tackle such diverse social problems as child abuse, disability, illiteracy, and environmental degradation give life to it." --Laura D'Andrea Tyson, Business Week
"This pioneering book details the development of social entrepreneurship globally with useful case studies and thoughtful analysis throughout. It represents one of the core teaching materials we use at Oxford."--Dr Alex Nicholls, Lecturer in Social Entrepreneurship, Said Business School, Oxford University
"One of the most powerful transformative forces in this century is social entrepreneurship and this book insightfully probes these entrepreneurial change agents driving this process. Enriching reading for students and practitioners seeking to build a better world."--James E. Austin, Snider Professor of Business Administration, Emeritus, and Co-Founder of the Harvard Business School Social Enterprise Initiative

About the Author
David Bornstein is a journalist who specializes in writing about social innovation. His first book, The Price of a Dream: The Story of the Grameen Bank was selected as a finalist for the New York Public Library Book Award for Excellence in Journalism. His articles have appeared in the Atlantic Monthly and the New York Times, and he co-wrote the P.B.S. documentary "To Our Credit." He lives in New York City.

Most helpful customer reviews

30 of 31 people found the following review helpful.
People Who Have Tried to Change the World
By dn4whtvr
Bornstein's "How to Change the World" is a love letter to Ashoka, an impressive and arguably very successful organization that identifies and supports social entrepreneurs throughout the world. Throughout the book, Bornstein provides a primer on Ashoka, its founder and methodology, as well as a number of success stories. He begins with a well-researched and interesting explanation about how the social entrepreneurship movement - or the citizen sector, as he calls it - found its sweet spot for expansion in the late 20th century. His narrative style is not nearly as compelling as first-person stories, such as "The Blue Sweater" (Novogratz, 2009), or even "Half the Sky" (Kristof & WuDunn, 2009). If each featured social entrepreneur had written a first-person account, this may have provided a more compelling read. One obviously missing component of Bornstein's vignettes is an acknowledgement of failure. On their respective roads to success, what significant missteps did these entrepreneurs take? What did they learn from those mistakes and failures?

This book may be a wonderful resource for people who are not yet familiar with social entrepreneurship or the amazing work that has been done by citizen sector individuals and organizations worldwide in the last 30 years. I appreciate the time Bornstein spent describing historical figures, demonstrating that social entrepreneurship is nothing new; it is simply finally getting the attention it deserves. However, the book falls short of its title. It is not a how-to. Although the resource list is well-balanced, and there are some nuggets of discussion of what it takes to be successful in social entrepreneurship, Bornstein falls short of providing insight for individuals who are wondering whether they have what it takes to be a social entrepreneur. Other than being passionate and obsessive, what else does it take? Do the vignettes provide actionable lessons learned for readers who are considering becoming social entrepreneurs, or who are already in the citizen sector but want to find more success? This reader was left wanting.

18 of 18 people found the following review helpful.
Who Will Be The Future Changemakers?
By Dance Aoki
Every person Bornstein discussed has the inspired capacity for solving intricate social problems resourcefully and efficiently, and they are able to maneuver around seemingly insurmountable obstacles to accomplish their goals.

James Grant of Unicef is particularly striking. His story illustrates how the provision of social services on a grand scale will be met with resistance, even if it is an easy one to distribute, is relatively inexpensive and could save thousands of lives. Grant never faltered, and activated his limited resources. As a result, he changed the world. Yet, there is a long road ahead on the mission towards immunizing all children against preventable diseases. Governments, investors, and all concerned citizens want to know the value of enterprises such as Unicef. Bornstein emphasizes in his conclusion that metrics for analyzing social value need to be developed in the civic sector in order to accurately evaluate the organization's ability to create social value. In the public health world, value is created in the number of sick individuals. The statistics that followed Grant's initiatives indicated lowered child mortality and improved qualities of life across the globe, which speak to the value of his work.

Each entrepreneur exemplifies the nature of their work in different ways. Bornstein succeeds in drawing connections between each Ashoka fellow and teases out a skeleton of what an effective social entrepreneur might look like. A new generation could be in the grooming process of inheriting the legacy that these fellows have built from scratch.

25 of 27 people found the following review helpful.
Bornstein and How to Change the World
By Cordlaine
Bornstein's book might not be what people are looking for when they initially pick it up, however, overall it has a diverse plot. The sections are all very different and cover a variety of different people and places. One of my favorite chapters was chapter 10, Are They Possessed, Really Possessed, by an Idea? I liked where the writers bring up a strong point about the term, 'social entrepreneurs.' The term social entrepreneur is new to many people around the world, I remember saying it to my roommates and they looked at me like I was mildly crazy. However, the term is relevant to a lifestyle and purpose of life for many people who live it. The lifestyle explained by Bornstein in this chapter explains the character of the entrepreneur doesn't announce themselves, they work hard to gather important and relevant information for the good of the project, not for the good of themselves. They want this earth to be a better place for the earth, not for themselves. This was a great point and helped me to view the book as extremely helpful. It shares a variety of different stories, and helps to put cultural differences into perspective. I am enjoying this book very much!

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[N671.Ebook] Download PDF New Femininities: Postfeminism, Neoliberalism and SubjectivityFrom Palgrave Macmillan

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New Femininities: Postfeminism, Neoliberalism and SubjectivityFrom Palgrave Macmillan

This collection of original essays looks at the way in which experiences and representations of femininity are changing, and explores the possibilities for producing 'new' femininities in the twenty-first century. The volume includes a Preface by leading feminist scholar Angela McRobbie.

  • Sales Rank: #975644 in Books
  • Published on: 2011-02-15
  • Released on: 2011-02-15
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.00" h x .81" w x 6.00" l, 1.40 pounds
  • Binding: Hardcover
  • 336 pages

Review

"This timely collection offers an extensive and thought-provoking range of insights into contemporary feminist debates around sexual subjectivity and citizenship, postfeminist identity and consumerism, and the constructions of femininity in relation to 'race', religion, migration, national security and generation. It represents both an important and refreshing contribution to the advancement of feminist media research." - Cynthia Carter, Cardiff University, UK

"New Femininities is an outstanding collection of theoretically rich and engaging essays that analyze how the global project of neoloberalism has coopted many of the basic tenets of feminism in corporately shrewd and often reactionary ways while selling all this as female empowerment. New Femininities is especially strong in showing how various media have worked to constitute new female subjectivities that are deeply contradictory. A very smart, timely and important anthology." - Susan J. Douglas, Professor of Communication Studies, University of Michigan, USA, and author of The Rise of Enlightened Sexism

"Rosalind Gill and Christina Scharff's edited collection, New Femininities: Postfeminism, Neoliberalism and Subjectivity, provides an excellent road map for understanding gender, contemporary media and pop culture today. Across twenty original essays, this book grapples with the pressures and opportunities afforded to women across a range of transnational media forms, including magazines, adverts, the web, reality TV shows, and diasporic cinema." - Feminist Memory, 2014

About the Author
FEONA ATTWOOD Lecturer Media and Communication Studies at Sheffield Hallam University, UK BRINDA BOSE Associate Professor of English at Delhi University, India SHELLEY BUDGEON Senior Lecturer in Sociology at the University of Birmingham, UK DAWN CURRIE Professor of Sociology at University of British Columbia, Canada UMUT EREL LISA GUERRERO Associate Professor in Comparative Ethnic Studies at Washington State University, USA JIN HARITAWORN Helsinki Collegium for Advanced Studies Fellow, University of Helsinki, Finland LAURA HARVEY PhD candidate at the Open University, UK SUE JACKSON Senior Lecturer in the School of Psychology at Victoria University of Wellington, New Zealand DEIRDRE M. KELLY Professor of Sociology of Education in the Department of Educational Studies, University of British Columbia, Canada JONGMI KIM Senior Lecturer at the Department of Media and Communication, Coventry University, UK MICHELLE M. LAZAR Associate Professor in the Department of English Language & Literature at the National University of Singapore CAROLYN PEDWELL Lecturer in Media and Cultural Studies at Newcastle University, UK SHAUNA POMERANTZ Assistant Professor of Child and Youth Studies at Brock University, Canada ANDREA PRESS Chair of the Department of Media Studies and Professor of Sociology at the University of Virginia, USA JESSICA RINGROSE Senior Lecturer at the Institute of Education, University of London, UK RÓISÍN RYAN-FLOOD Lecturer in Sociology and Director of the Centre for Intimate and Sexual Citizenship (CISC) at the University of Essex, UK ESTELLA TINCKNELL Reader in Media and Cultural Studies at the University of the West of England, Bristol, UK IMOGEN TYLER Lecturer in Sociology at Lancaster University, UK TIINA VARES Senior Lecturer in Sociology and Gender Studies at the University of Canterbury, UK SADIE WEARING Lecturer in Gender Theory, Culture and Media at the Gender Institute, London School of Economics, UK

Most helpful customer reviews

2 of 2 people found the following review helpful.
Mixed Feelings
By Post Post Minimal
This is an important topic and there are some OK texts. I don't see a lot of alternatives that have been published so I would still buy this if you are very interested in the subject, but I would first recommend "Interrogating Postfeminism: Gender and the Politics of Popular Culture" by Yvonne Tasker and Diane Negra and "The Aftermath of Feminism: Gender, Culture and Social Change" by Angela McRobbie.

I felt like many of the essays were too short, and ended just as they were approaching substantial ideas. Many of the essays are sketches for proposed case studies or more in depth research. I haven't looked into the credentials of contributors but some of the texts read as if they were written by PhD students. That being said, I really enjoyed some sections, especially "Pregnant Beauty" by Imogen Tyler. I could imagine using some of these essays in an undergraduate course, I just wouldn't assign the entire book.

I don't think Rosalind Gill should have edited this book. I find it really strange that almost every essay prominently cites her texts, it seems like a conflict of interest and makes me suspicious of the integrity of the collection. This certainly reflects the fact that this is a niche field, but bothers me none the less.

There isn't enough written about neoliberalism and postfeminism, and I wanted to love this book, but I did not.

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Selasa, 01 Juli 2014

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Errata Notice: Sanford Guide to Antimicrobial Therapy 2016:
Print Edition Content Notices (shipped prior to 5/11/16) Antibacterial Activity Spectra (Table 4, p78):
A column shift caused activity data to be displayed incorrectly for Linezolid, Tedizolid, Rifampin (combination), TMP-SMX, Fosfomycin and Metronidazole vs. Anaerobic gram-positive bacteria (the lower right quadrant of the page). A sticker is available to replace the page:
http: //www.sanfor dguide.com/support/errata

  • Sales Rank: #354264 in Books
  • Published on: 2016-04-01
  • Original language: English
  • Dimensions: 10.90" h x .50" w x 7.20" l, .0 pounds
  • Binding: Paperback
  • 254 pages

Most helpful customer reviews

3 of 3 people found the following review helpful.
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